2005 database to restore on 2008R2 server

Hi,

I have a couple of databases on Sql 2005 (w 2003 server). 

I want to have them (start with one) on a different SQL server (sql 2008R2 on w 2008R2).

I saw a few kBs but still not sure what is the simplest way to go about that. Would appreciate if anyone can give some suggestions or steps. 

Not sure it matters, but both these servers are on different domains. People access these databases via ODBC connection using SQL server authentication (not windows), which will be same on the new server as well.

Thanks,

Ashok